Publications
Knowledge generated at IrsiCaixa is shared with the scientific community through the publication of articles in high impact scientific journals.
Secretion of interferon-gamma by human macrophages demonstrated at the single-cell level after costimulation with interleukin (IL)-12 plus IL-18.
Quantitative deep sequencing reveals dynamic HIV-1 escape and large population shifts during CCR5 antagonist therapy in vivo.
A dynamic target-based pharmacophoric model mapping the CD4 binding site on HIV-1 gp120 to identify new inhibitors of gp120-CD4 protein-protein interactions.
Transmission of drug-resistant HIV-1 is stabilizing in Europe.
HIV-1 gp41 fusogenic function triggers autophagy in uninfected cells.
Immune-driven recombination and loss of control after HIV superinfection.
HIV-1 resistance to the anti-HIV activity of a shRNA targeting a dual-coding region.
Increased cytotoxic T-lymphocyte epitope variant cross-recognition and functional avidity are associated with hepatitis C virus clearance.
Variability in the plasma concentration of efavirenz and nevirapine is associated with genotypic resistance after treatment interruption.
HIV-1 escape to CCR5 coreceptor antagonism through selection of CXCR4-using variants in vitro.