Publications
Knowledge generated at IrsiCaixa is shared with the scientific community through the publication of articles in high impact scientific journals.
Computational studies identifying entry inhibitor scaffolds targeting the Phe43 cavity of HIV-1 gp120.
Insights from host genomics into HIV infection and disease: Identification of host targets for drug development.
Worldwide population distribution of the common LCE3C-LCE3B deletion associated with psoriasis and other autoimmune disorders.
Differential prevalence of the HLA-C -- 35 CC genotype among viremic long term non-progressor and elite controller HIV+ individuals.
Rare LEDGF/p75 genetic variants in white long-term nonprogressor HIV+ individuals.
Trans-infection but not infection from within endosomal compartments after cell-to-cell HIV-1 transfer to CD4+ T cells.
Antiretroviral agents effectively block HIV replication after cell-to-cell transfer.
Compensatory mutations rescue the virus replicative capacity of VIRIP-resistant HIV-1.
β5 integrin is the major contributor to the αVintegrin-mediated blockade of HIV-1 replication.
Development of resistance to VIR-353 with cross-resistance to the natural HIV-1 entry virus inhibitory peptide (VIRIP).