Publications
Knowledge generated at IrsiCaixa is shared with the scientific community through the publication of articles in high impact scientific journals.
Polymorphic LEDGF/p75 variants support efficient HIV-1 infection ex vivo.
Insights from host genomics into HIV infection and disease: Identification of host targets for drug development.
HLA class I protective alleles in an HIV-1-infected subject homozygous for CCR5-Δ32/Δ32.
Nucleotide embargo by SAMHD1: a strategy to block retroviral infection.
The cortical actin determines different susceptibility of naïve and memory CD4+ T cells to HIV-1 cell-to-cell transmission and infection.
Differential prevalence of the HLA-C -- 35 CC genotype among viremic long term non-progressor and elite controller HIV+ individuals.
Rare LEDGF/p75 genetic variants in white long-term nonprogressor HIV+ individuals.
Trans-infection but not infection from within endosomal compartments after cell-to-cell HIV-1 transfer to CD4+ T cells.
Antiretroviral agents effectively block HIV replication after cell-to-cell transfer.
Development of resistance to VIR-353 with cross-resistance to the natural HIV-1 entry virus inhibitory peptide (VIRIP).