Publications
Knowledge generated at IrsiCaixa is shared with the scientific community through the publication of articles in high impact scientific journals.
Significant changes in integrase-associated HIV-1 replication capacity between early and late isolates.
Quasispecies Dynamics of RNA Viruses
Canine hepacivirus NS3 serine protease can cleave the human adaptor proteins MAVS and TRIF.
Evolution of the human immunodeficiency virus type 1 protease: effects on viral replication capacity and protease robustness.
Deciphering the interleukin 28B variants that better predict response to pegylated interferon-α and ribavirin therapy in HCV/HIV-1 coinfected patients.
Complexity and catalytic efficiency of hepatitis C virus (HCV) NS3 and NS4A protease quasispecies influence responsiveness to treatment with pegylated interferon plus ribavirin in HCV/HIV-coinfected patients.
IL28B SNP rs8099917 is strongly associated with pegylated interferon-α and ribavirin therapy treatment failure in HCV/HIV-1 coinfected patients.
Epistasis among deleterious mutations in the HIV-1 protease.
Mechanistic basis of zidovudine hypersusceptibility and lamivudine resistance conferred by the deletion of codon 69 in the HIV-1 reverse transcriptase coding region.
HIV-1 protease catalytic efficiency effects caused by random single amino acid substitutions.