RANDOMISED CLINICAL TRIAL TO ASSESS THE IMPACT OF ORAL INTERVENTION WITH CETYLPYRIDINIUM CHLORIDE (CPC) TO REDUCE SALIVARY SARS-CoV-2 VIRAL LOAD.

Background: Aerosols released from the oral cavity help spread the SARS-CoV-2 virus. The use of a mouthwash formulated with an antiviral agent could reduce the viral load in saliva, helping to lower the spread of the virus.

Results: By means of RT-qPCR, no significant differences were observed between the placebo group and the test group. However, 2 hours after a single rinse N protein concentration in saliva was significantly higher in the test group, indicating an increase in lysed virus.

Conclusion: By means of RT-qPCR, no significant differences were observed between the placebo group and the test group. However, 2 hours after a single rinse N protein concentration in saliva was significantly higher in the test group, indicating an increase in lysed virus.