Publicaciones
El conocimiento generado en IrsiCaixa se comparte con la comunidad científica a través de la publicación de artículos en revistas científicas de alto impacto.
Gene editing using a zinc-finger nuclease mimicking the CCR5Δ32 mutation induces resistance to CCR5-using HIV-1.
Increased expression of SAMHD1 in a subset of HIV-1 elite controllers.
Zinc finger endonuclease targeting PSIP1 inhibits HIV-1 integration.
Cell cycle control and HIV-1 susceptibility are linked by CDK6-dependent CDK2 phosphorylation of SAMHD1 in myeloid and lymphoid cells.
Characterization of the influence of mediator complex in HIV-1 transcription.
p21 regulates the HIV-1 restriction factor SAMHD1.
Polymorphic LEDGF/p75 variants support efficient HIV-1 infection ex vivo.
Insights from host genomics into HIV infection and disease: Identification of host targets for drug development.
HLA class I protective alleles in an HIV-1-infected subject homozygous for CCR5-Δ32/Δ32.
Nucleotide embargo by SAMHD1: a strategy to block retroviral infection.